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Susan J Knox Selected Research

Radiation-Sensitizing Agents

4/2016Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial: A TITE-CRM Phase I/II Clinical Trial.
12/2013Radioprotection and cell cycle arrest of intestinal epithelial cells by darinaparsin, a tumor radiosensitizer.
6/2012Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer.
5/2012Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials.
12/2010Anti-tumor and radiosensitization activities of the iron chelator HDp44mT are mediated by effects on intracellular redox status.
9/2010Sodium selenite radiosensitizes hormone-refractory prostate cancer xenograft tumors but not intestinal crypt cells in vivo.

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Susan J Knox Research Topics

Disease

49Neoplasms (Cancer)
06/2021 - 01/2002
10Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2013 - 12/2003
8Prostatic Neoplasms (Prostate Cancer)
06/2021 - 12/2003
8Melanoma (Melanoma, Malignant)
02/2020 - 10/2004
4Neoplasm Metastasis (Metastasis)
12/2018 - 10/2010
4Hypoxia (Hypoxemia)
12/2015 - 05/2012
3Pain (Aches)
06/2021 - 09/2015
3Brain Neoplasms (Brain Tumor)
04/2016 - 06/2006
3Carcinoma (Carcinomatosis)
09/2010 - 01/2002
2Colonic Neoplasms (Colon Cancer)
01/2017 - 06/2006
2Lymphoma (Lymphomas)
10/2010 - 10/2005
2Anemia
08/2007 - 01/2005
1Genetic Predisposition to Disease (Genetic Predisposition)
12/2020
1Stomatitis
10/2020
1Rectal Neoplasms (Rectal Cancer)
01/2020
1Microsatellite Instability
01/2020
1Hypophysitis
12/2018
1Metabolic Bone Diseases (Osteopenia)
12/2018
1Pathologic Complete Response
12/2018
1Skin Diseases (Skin Disease)
12/2013
1Radiodermatitis
07/2012
1Dermatitis
07/2012

Drug/Important Bio-Agent (IBA)

7RRx-001IBA
01/2017 - 08/2015
7Monoclonal AntibodiesIBA
02/2015 - 04/2003
6Radiation-Sensitizing AgentsIBA
04/2016 - 09/2010
5Selenious Acid (Selenite)IBA
06/2021 - 01/2005
5IpilimumabIBA
02/2020 - 12/2012
5Oxygen (Dioxygen)IBA
04/2016 - 04/2012
4Radioisotopes (Radionuclides)IBA
01/2021 - 04/2003
4IntegrinsIBA
10/2010 - 10/2004
3Sodium SeleniteIBA
06/2021 - 09/2010
3Proteins (Proteins, Gene)FDA Link
01/2020 - 12/2003
3Antineoplastic Agents (Antineoplastics)IBA
01/2017 - 05/2012
3NitrogenIBA
12/2015 - 08/2015
3Pharmaceutical PreparationsIBA
12/2015 - 04/2003
3Arsenic Trioxide (Trisenox)FDA Link
06/2012 - 09/2004
3Integrin alphaVbeta3IBA
06/2008 - 03/2004
3AntigensIBA
06/2006 - 04/2003
2Prostate-Specific Antigen (Semenogelase)IBA
06/2021 - 11/2008
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2020 - 01/2002
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2020
2Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2015 - 05/2014
2Histones (Histone)IBA
12/2015 - 09/2015
2EnzymesIBA
08/2015 - 08/2010
2Cisplatin (Platino)FDA LinkGeneric
05/2014 - 05/2012
2Cytotoxins (Cytolysins)IBA
12/2013 - 06/2012
2darinaparsinIBA
12/2013 - 06/2012
2ArsenicIBA
12/2013 - 06/2012
2ibritumomab tiuxetan (Zevalin)FDA Link
06/2013 - 04/2010
2Integrin alphaVIBA
10/2010 - 06/2008
2Neoplasm Antigens (Tumor Antigens)IBA
10/2010 - 12/2003
2intetumumabIBA
10/2010 - 06/2008
2Hormones (Hormone)IBA
09/2010 - 08/2006
2tositumomab I-131 (Bexxar)FDA Link
04/2010 - 10/2005
2Selenium CompoundsIBA
11/2008 - 01/2005
2SeleniumIBA
11/2008 - 08/2006
2AndrogensIBA
11/2008 - 01/2005
2Androgen Receptors (Androgen Receptor)IBA
11/2008 - 08/2006
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2008 - 01/2002
2AntibodiesIBA
01/2006 - 04/2003
2IodineIBA
06/2005 - 12/2004
1RadiopharmaceuticalsIBA
01/2021
1Epidermal Growth Factor (EGF)IBA
10/2020
1Heparin (Liquaemin)FDA LinkGeneric
10/2020
1Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
10/2020
1Immune Checkpoint InhibitorsIBA
04/2020
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2020
1CarcinogensIBA
01/2020
1NivolumabIBA
01/2020
1flt3 ligand protein (flt3 ligand)IBA
01/2020
1Salivary alpha-AmylasesIBA
01/2020
1GlucocorticoidsIBA
12/2018
1NADP (NADPH)IBA
01/2017
1DNA (Deoxyribonucleic Acid)IBA
01/2017
1Antiviral Agents (Antivirals)IBA
01/2017
1MethyltransferasesIBA
01/2017
1Reactive Nitrogen SpeciesIBA
04/2016
1Lysine (L-Lysine)FDA Link
09/2015
1AntioxidantsIBA
08/2015
1Renilla LuciferasesIBA
08/2015
1Firefly LuciferasesIBA
08/2015
1Immunomodulating AgentsIBA
12/2014
1glycidyl nitrateIBA
05/2014
1Hypochlorous Acid (Hypochlorite)IBA
12/2013
1Cancer VaccinesIBA
12/2012
1Aldehyde DehydrogenaseIBA
07/2012
1AldehydesIBA
07/2012
14-hydroxy-2-nonenal (4-hydroxynonenal)IBA
07/2012
11-bromoacetyl-3,3-dinitroazetidineIBA
05/2012

Therapy/Procedure

25Radiotherapy
06/2021 - 01/2002
18Therapeutics
01/2021 - 09/2004
6Drug Therapy (Chemotherapy)
10/2020 - 09/2004
6Immunotherapy
12/2018 - 12/2003
6Radioimmunotherapy
06/2013 - 12/2003
3Aftercare (After-Treatment)
11/2019 - 10/2010
2Chemoradiotherapy
01/2020 - 08/2004
1Precision Medicine
12/2020
1Neoadjuvant Therapy
01/2020
1Induction Chemotherapy
01/2020
1Transplantation
07/2013